Medication use in pregnancy: a cross-sectional, multinational web-based study
Lupattelli, A; Spigset, O; Twigg, MJ; Zagorodnikova, K; Nårdby, AC; Moretti, ME; Drozd, M; Panchaud, A; Hämeen-Anttila, K; Rieutord, A; Gjergija Juraski, R; Odalovic, M; Kennedy, D; Rudolf, G; Juch, H; Passier, A; Björnsdottir, I; Nordeng, H (2014)
Tätä artikkelia/julkaisua ei ole tallennettu Julkariin. Julkaisun tiedoissa voi kuitenkin olla linkki toisaalle tallennettuun artikkeliin/julkaisuun.
Lupattelli, A
Spigset, O
Twigg, MJ
Zagorodnikova, K
Nårdby, AC
Moretti, ME
Drozd, M
Panchaud, A
Hämeen-Anttila, K
Rieutord, A
Gjergija Juraski, R
Odalovic, M
Kennedy, D
Rudolf, G
Juch, H
Passier, A
Björnsdottir, I
Nordeng, H
2014
BMJ Open
Tiivistelmä
Objectives: Intercountry comparability between
studies on medication use in pregnancy is difficult due
to dissimilarities in study design and methodology.
This study aimed to examine patterns and factors
associated with medications use in pregnancy from a
multinational perspective, with emphasis on type of
medication utilised and indication for use.
Design: Cross-sectional, web-based study performed
within the period from 1 October 2011 to 29 February
2012. Uniform collection of drug utilisation data was
performed via an anonymous online questionnaire.
Setting: Multinational study in Europe (Western, Northern
and Eastern), North and South America and Australia.
Participants: Pregnant women and new mothers with
children less than 1 year of age.
Primary and secondary outcome measures:
Prevalence of and factors associated with medication use
for acute/short-term illnesses, chronic/long-term disorders
and over-the-counter (OTC) medication use.
Results: The study population included 9459 women,
of which 81.2% reported use of at least one medication
(prescribed or OTC) during pregnancy. Overall, OTC
medication use occurred in 66.9% of the pregnancies,
whereas 68.4% and 17% of women reported use of at
least one medication for treatment of acute/short-term
illnesses and chronic/long-term disorders, respectively.
The extent of self-reported medicated illnesses and types
of medication used by indication varied across regions,
especially in relation to urinary tract infections, depression
or OTC nasal sprays. Women with higher age or lower
educational level, housewives or women with an unplanned
pregnancy were those most often reporting use of
medication for chronic/long-term disorders. Immigrant
women in Western (adjusted OR (aOR): 0.55, 95% CI 0.34
to 0.87) and Northern Europe (aOR: 0.50, 95% CI 0.31 to
0.83) were less likely to report use of medication for
chronic/long-term disorders during pregnancy than nonimmigrants.
Conclusions: In this study, the majority of women in
Europe, North America, South America and Australia used
at least one medication during pregnancy. There was a
substantial inter-region variability in the types of medication
used.
studies on medication use in pregnancy is difficult due
to dissimilarities in study design and methodology.
This study aimed to examine patterns and factors
associated with medications use in pregnancy from a
multinational perspective, with emphasis on type of
medication utilised and indication for use.
Design: Cross-sectional, web-based study performed
within the period from 1 October 2011 to 29 February
2012. Uniform collection of drug utilisation data was
performed via an anonymous online questionnaire.
Setting: Multinational study in Europe (Western, Northern
and Eastern), North and South America and Australia.
Participants: Pregnant women and new mothers with
children less than 1 year of age.
Primary and secondary outcome measures:
Prevalence of and factors associated with medication use
for acute/short-term illnesses, chronic/long-term disorders
and over-the-counter (OTC) medication use.
Results: The study population included 9459 women,
of which 81.2% reported use of at least one medication
(prescribed or OTC) during pregnancy. Overall, OTC
medication use occurred in 66.9% of the pregnancies,
whereas 68.4% and 17% of women reported use of at
least one medication for treatment of acute/short-term
illnesses and chronic/long-term disorders, respectively.
The extent of self-reported medicated illnesses and types
of medication used by indication varied across regions,
especially in relation to urinary tract infections, depression
or OTC nasal sprays. Women with higher age or lower
educational level, housewives or women with an unplanned
pregnancy were those most often reporting use of
medication for chronic/long-term disorders. Immigrant
women in Western (adjusted OR (aOR): 0.55, 95% CI 0.34
to 0.87) and Northern Europe (aOR: 0.50, 95% CI 0.31 to
0.83) were less likely to report use of medication for
chronic/long-term disorders during pregnancy than nonimmigrants.
Conclusions: In this study, the majority of women in
Europe, North America, South America and Australia used
at least one medication during pregnancy. There was a
substantial inter-region variability in the types of medication
used.
Kokoelmat
- Artikkelit [186]